The environment profoundly conditions our biology, and by environment we must understand both the external environment and the landscape, social, food, air, water .. but also the internal one. The internal environment is made up of actions and reactions, the visual channels of external and internal impulses, thoughts, emotions (therefore our mind) obviously not forgetting the whole chemical component.
The epigenetic programming of gene expression is sensitive to the environment from the early stages of life, so both the social and chemical environments can influence the way the genome is programmed.
Studies show that adversity in the early stages of life leaves its mark on our epigenome and influences, in adult life, reactivity to stress and health, both physical and mental.
Similarly, it is now clear that even adults respond epigenetically to environmental signals, which influence the physiology, behavior and risk of disease.
Isn't this what Ayurveda says?
According to Ayurveda the longevity and quality of life depend on factors: daiva and purushakara.
The daiva are the actions performed now and in the past (the past kharma we can see it as our DNA) while the purushakara is what we do in this life. All external factors such as time, climate, nutrition, emotional state, human relationships, social circumstances, age, time of day ... constantly alter the energy composition of the body. Ayurveda teaches many methods to learn to maintain this balance in us according to the individual constitution and circumstances of life.

Kharma and Epigenetics
By acting on our thoughts, on our mind, on our perception of the external world and how we will let it interact with us, we will modify our cellular memory, our DNA, our baggage of remote experiences, our Kharma.
Acting on our thinking, on our future visualization we will change the present and consequently the past, because as quantum physics shows us in reality space and time do not exist; past, present and future are one, only that we are in an awareness that perceives only time in one direction.
In reality, coming to understand our action on action through the mind, we will understand how we can modify our "destiny", our Kharma.
The term Kharma derives from the Sanskrit root kr which means "to do, to perform, to produce, to act, to move" therefore everything but immobile and established.
So action is both cause and effect and in this sense all the actions of the body, mind and senses: attraction, repulsion, walking, talking, seeing, listening, thinking and desiring, etc. they are karma, therefore subject to the law of causality.
Many think that by accepting the doctrine of karma, one accepts accordingly a fatalistic and predeterminism doctrine.
On the contrary, one can produce or modify one's karma by taking life in one's own hands, and becoming masters of one's destiny.
There is a logical continuity in the law of cause and effect. It is possible to know how a specific action, developing through a chain of cause and effect, influences our life.
"Sow a thought, take an action
Sow an action, collect a habit
Sow a habit, collect a character
Sow a character, collect a destiny.
(Law of Kharma)
The environment changes genes
In recent years, however, it has been scientifically discovered that the environment influences genes.
However, we have a genetic set that is extremely sensitive to the external and internal environment that responds by turning on or off, activating or not.
For this reason the term EPIGENETICA has been coined for at least 30 years.
Ep (i) from the Greek means above, which generates, then study of what is above, above the genes and controls gene expression with the synthesis of proteins.
This something is a complex of molecules that are activated in a certain way and on the basis of certain stimuli determine the turning on or off of certain genes.
Epigenetic regulation goes from pimple to neoplasm, passing through every visible expression

What has been understood about cancer with epigenetics?

The American Society of Oncology has affirmed that only for 5% of the tumors one can speak of "familiarity" and that therefore 95% of them has no genetic connection, they depend instead on the lifestyle .. therefore they have an epigenetic modulation!
The head of the Epidemiology and Genetics Unit of the Milan Polyclinic said, in a recent study published in genetic magazines, that "... many people monitored by them, and resulting carriers of a cancer gene, do not actually develop the illness!"
Most malignant tumors are caused by epigenetic alterations induced by the environment and not by defective genes (Kling 2003, Jones 2001, Speea 2000, Baylin 1997)
Biologist Marion Lamb and philosopher Eva Jablonka write in a 1995 study:
Recent molecular biology has shown that the genome is much more ductile and reactive to the environment than previously thought
DNA therefore does not control biological processes, and the nucleus is not the brain of the cell. The cells are shaped by the environment in which they live .. from what Lipton defines STUPID ENVIRONMENT.

What is then influenced by our life choices and how do we perceive emotional stimuli?

We are born, not as a blank sheet, but with genetic heritage that has already been somehow modulated throughout the gestation .. when we come to the world then also begins the strong external conditioning made by choices, emotional memories that we are going to deposit in the conscious and unconscious to which we draw whenever a stimulus presents itself ... like a book of memories that serves to activate an adequate response. On the basis of our experiences we therefore create a data warehouse, consolidate habits that we will hardly have the courage or even the simple thought of modifying.
A circular path, a revolving door: habits → thoughts → emotions → choices → habits ...
Let us remember that basic emotions are energy, reactions to stimuli (external or internal) but if repressed and maintained they become toxic.
So toxic, emotionally toxic habits affect us and our health with epigenetic modulation.
It therefore becomes important to succeed and to reformulate .. to create new neural pathways, new mental associations.